“I guess you should approach the roles differently when they're actual people who have been, this is the difference. Getting the accent exact, or the hair exact is less important in a situation like this.”
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She came up with a whole way of doing fluoroscopy, which is kind of like a live version of X-ray, so that she could see the heart as it worked, not frozen in a picture.
Mary Stuart Masterson 
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What is more important is finding the soul of the character, and making sure it fits well into this story. And that it be dramatic and interesting and captivating, because these people weren't entertainers, you know.
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Just the actual physical ability to hold four instruments simultaneously and do some of the things that Vivien was able to do is mind blowing to any surgeon. He never went to medical school and he became one of the great teachers of medicine himself, people are just amazed.
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